TPE Foundations Online
The Complete Physician Training for Therapeutic Plasma Exchange
The online training program that teaches physicians how to evaluate, implement, and build a therapeutic plasma exchange practice is coming soon.
TPE Foundations Online is a comprehensive, self-paced course designed by Ryan Bentley, MD, PhD, DC, covering the science, the clinical protocols, the patient selection process, and the business model behind therapeutic plasma exchange.
This course was built for physicians who want to offer their patients something most doctors have never been trained on: the ability to remove what is making them sick.
A Peek Into the Training Modules
This course was built for physicians who want to offer their patients something most doctors have never been trained on: the ability to remove what is making them sick. The training walks through the science, clinical implementation, and real-world application of therapeutic plasma exchange.
- The mechanism behind therapeutic plasma exchange
- Why parabiosis research changed plasma biology
- Identifying the right patients in your practice
- Procedure walkthrough, equipment, and room setup
- Advanced applications: toxins, autoimmune, neuro, sports medicine
- Real case studies with biomarker outcomes
Module 1: Foundations of Therapeutic Plasma Exchange
The mechanism of action, the history of TPE, FDA-approved and emerging indications, and the parabiosis and plasma dilution research that changed our understanding of why plasma quality determines cellular function.
Module 2: Patient Selection and Assessment
Who is a candidate for TPE and who is not. The complete diagnostic workup including environmental toxin panels, genetic testing, advanced biomarkers, candidacy criteria, informed consent, and CPT coding.
Module 3: The Procedure
The Fresenius Kabi Spectra Optia system, room setup, vascular access options, and a step-by-step walkthrough of a complete TPE session from patient preparation through post-procedure monitoring.
Module 4: Advanced Applications
Environmental toxin removal protocols, autoimmune disease management, neurological applications, sports medicine integration, and combining TPE with precision medicine interventions.
Module 5: Building Your Practice
The business model behind TPE including equipment sourcing, staffing, marketing to patients and physicians, billing, compliance, and positioning TPE within a precision medicine practice.
Module 6: Case Studies
De-identified patient cases including diagnostic workups, treatment protocols, and measured pre-and-post biomarker results across environmental toxin, autoimmune, neurological, and performance optimization cases.
Be the First to Know When Enrollment Opens
No spam. You will receive one email when the course goes live, along with early-access pricing details available only to this list.
Ryan Bentley, MD, PhD, DC
Dr. Bentley is a physician-scientist who holds three doctorate degrees: an MD, a PhD in Biomedical Sciences with a focus on photobiomodulation, and a DC. He serves as Clinical Assistant Professor at Western Michigan University Homer Stryker M.D. School of Medicine and operates Vitalis-Health in Holland, Michigan.
He provides precision health services to professional athletes including NFL players. His clinical practice centers on therapeutic plasma exchange, environmental toxin assessment, and precision medicine guided by advanced genetic and biomarker testing.
Dr. Bentley has trained physicians across the country to add TPE to their practices and is the author of multiple books on health optimization.

Questions about the course? Email info@vitalis-health.com
